Head to Old Town Square, admire the Gothic Týn Church and the colorful historic buildings.
Watch the Astronomical Clock strike the hour, walk to Charles Bridge in the late afternoon, which is lined with statues and street artists, and cross to the Lesser Town side.
DAY 02
Prague Castle and Lesser Town
Start early at Prague Castle, the largest ancient castle complex in the world, Visit St. Vitus Cathedral, the Old Royal Palace and the narrow Golden Lane inside the castle grounds.
Take the funicular up Petřín Hill in the evening for sunset views and a walk to the small lookout tower.
DAY 03
Jewish Quarter and Vltava River
Explore the Jewish Quarter (Josefov) in the morning to see the synagogues and the Old Jewish Cemetery.
Walk along the river to the Dancing House, then continue to Vyšehrad Fortress for peaceful views of the city and the Vltava.
Take an evening river cruise on the Vltava to see the illuminated castle and bridges.
DAY 04
Brno
Visit Špilberk Castle, a hilltop fortress with a museum and great city views.
Walk down to Freedom Square and the Cabbage Market, then climb the tower of the Old Town Hall.
DAY 05
Brno Culture
Visit the Cathedral of St. Peter and Paul in the morning, then head underground to the Capuchin Crypt and the Brno Ossuary.
See Villa Tugendhat, a UNESCO-listed modernist house, and book your ticket in advance as slots fill up quickly.
